Make sure you always retain control of your domain name. There are hundreds of businesses hosting their websites with a web host they’re not happy with. Poor service, surprise invoices, unreliable uptime and email issues are just some of the common issues customers are facing today. What most of them want to do is vote with their feet and walk out the door and find another web hosting provider. They don’t go through with it, however, because moving all their domains to another host is a complete admin headache. Choose wisely from the get-go so you don’t become one of these customers.
When looking up a bare name in DNS, the network stack will add the search domains to it to form fully qualified domain names, and look up those as well. For example, if the domain search list contains "wikipedia.org", typing "en" in the browser will direct the user to "en.wikipedia.org". Some ISPs add their own search domains via DHCP settings, similar to how they add DNS servers and other networking information; if this is undesired, the user can change this setting to ".local".
Make sure you can use their SMTP servers for outgoing email. Many hosting and domain name registration providers will not let you use their SMTP servers for sending emails. They assume you can send email via your internet server provider’s SMTP servers. However, a great many ISPs and broadband providers will only let you use their SMTP servers on their branded email accounts (i.e. [email protected]). This means that if you use your own email address (i.e. [email protected]), you won’t be able to send email via their SMTP servers. There are workarounds but you shouldn’t have to go to the trouble.
Many online shops have the number 24 in them, to signify 24 hours a day – you may also be able to integrate numbers into your domain in a meaningful way to make them unique. Be careful though, because many cultures attach a lot of significance to certain numbers. Make sure that your number doesn't represent bad luck or other negative things in the country you're operating in.