Make sure you can use their SMTP servers for outgoing email. Many hosting and domain name registration providers will not let you use their SMTP servers for sending emails. They assume you can send email via your internet server provider’s SMTP servers. However, a great many ISPs and broadband providers will only let you use their SMTP servers on their branded email accounts (i.e. [email protected]). This means that if you use your own email address (i.e. [email protected]), you won’t be able to send email via their SMTP servers. There are workarounds but you shouldn’t have to go to the trouble.
A short, one-word name (ex. cat.com), and especially .com domains, will be pricy because simple titles have a lot of potential uses, meaning people probably already check them out on their own. If you are going after a registered .com domain, you will have to contact the current owner, and even then, prices could be high for misspellings and multiple word domains. In the past years, companies and individuals have settled for bizarre names, misspellings, and old tricks like adding “the” or “my” to the front; note, however, that this will also reduce domain performance. 

Many online shops have the number 24 in them, to signify 24 hours a day – you may also be able to integrate numbers into your domain in a meaningful way to make them unique. Be careful though, because many cultures attach a lot of significance to certain numbers. Make sure that your number doesn't represent bad luck or other negative things in the country you're operating in.

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