Be extremely cautious while communicating with the owner. Even if you casually agree to buy the domain via email, the communication might be used against you in court as a legally-binding contract should you change your mind. Until you’re absolutely certain that you want to make a deal, agree to buy the domain provided that all the terms are agreeable. This will leave you an escape hatch if things go south.
By definition, a domain name is simply a human readable form of an IP address. In function it is the destination that you type into a web browser in order to visit a website, such a www.google.com. Metaphorically, it is very similar to how you would scroll to a contact in your cell phone rather than manually dialing the person by entering their full phone number; the phone number would be an IP address and the saved contact would be a domain name. Always buy a domain with a reputable domain registrar.
Contact the owner. Before so much as hinting at a price, simply email to ask whether or not the domain is for sale. If you are known or can clearly be linked to a thriving business, create a generic alternate email address through which to contact them, as your success might be leveraged against you. Be aware, however, that an informal-sounding email address is more likely to be regarded as spam or junk mail.
Many online shops have the number 24 in them, to signify 24 hours a day – you may also be able to integrate numbers into your domain in a meaningful way to make them unique. Be careful though, because many cultures attach a lot of significance to certain numbers. Make sure that your number doesn't represent bad luck or other negative things in the country you're operating in.