A short, one-word name (ex. cat.com), and especially .com domains, will be pricy because simple titles have a lot of potential uses, meaning people probably already check them out on their own. If you are going after a registered .com domain, you will have to contact the current owner, and even then, prices could be high for misspellings and multiple word domains. In the past years, companies and individuals have settled for bizarre names, misspellings, and old tricks like adding “the” or “my” to the front; note, however, that this will also reduce domain performance.
Even if the term isn’t trademarked, don’t buy domains that are just a variation of another domain name. This means avoiding plurals if the singular is taken (mediatemple.net vs. mediatemples.net), hyphenating a phrase (media-temple.net), or adding “my” or some other preposition (mymediatemple.net). Alternately, you might consider buying these variations yourself and set them up so that if someone types one of the variations, they are redirected to your main site. 

A short, one-word name (ex. cat.com), and especially .com domains, will be pricy because simple titles have a lot of potential uses, meaning people probably already check them out on their own. If you are going after a registered .com domain, you will have to contact the current owner, and even then, prices could be high for misspellings and multiple word domains. In the past years, companies and individuals have settled for bizarre names, misspellings, and old tricks like adding “the” or “my” to the front; note, however, that this will also reduce domain performance.
Many online shops have the number 24 in them, to signify 24 hours a day – you may also be able to integrate numbers into your domain in a meaningful way to make them unique. Be careful though, because many cultures attach a lot of significance to certain numbers. Make sure that your number doesn't represent bad luck or other negative things in the country you're operating in.
Every website on the internet has a unique IP address assigned to it, made up of a series of numbers. These numbers tell the domain name system (DNS) to locate the corresponding website. As we are humans and not computers, IP addresses are difficult to remember and so words are used instead. These words are known as the domain or URL. The DNS looks at the domain name and translates it into an IP address.
The Internet Corporation for Assigned Names and Numbers (ICANN) is the organization that governs the rules and regulations for domain name registrations. ICANN requires, for various reasons including to determine ownership of a domain should a dispute transpire, that a publicly accessible database be maintained that contains the contact information of all domain registrants. In layman's terms this means your domain name will be searchable by anyone and those search results will include your full name, physical address and other contact information. In order to protect your privacy in this regard, Domain.com offers WHOIS Domain Privacy which then masks your information using our own and implements a procedure for you to control who is able to then gain access to your contact information via a WHOIS search. Whenever you buy a domain name, no matter what domain name registration service you use, you are subject to the same ICANN rules, for this reason it is important to use a reputable service who cares about your privacy. Domain.com always recommends enabling WHOIS Domain Privacy.
Make sure you can use their SMTP servers for outgoing email. Many hosting and domain name registration providers will not let you use their SMTP servers for sending emails. They assume you can send email via your internet server provider’s SMTP servers. However, a great many ISPs and broadband providers will only let you use their SMTP servers on their branded email accounts (i.e. [email protected]). This means that if you use your own email address (i.e. [email protected]), you won’t be able to send email via their SMTP servers. There are workarounds but you shouldn’t have to go to the trouble. 

If your purpose in buying a trademarked term as a domain name is to try to confuse people, you’re opening yourself up to having a complaint filed against you and having to give up the domain name. Even if you’re not trying to create confusion, you’re likely to face some legal challenges by buying trademarked terms in your domain name. To be safe, you can search for U.S. trademarks at www.uspto.gov and make sure no one owns a trademark on the name you are considering. 
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