It's good to decide early on if you want to have a brand domain or a keyword domain. The benefit of a brand domain is that your domain will most likely be considered as trustworthy, and immediately shows visitors that it's linked to your business or personal blog. A keyword domain, on the other hand, has the advantage that it will be better optimized for search engines, and therefore will get higher search results. In recent years, however, the drastic improvement in search results thanks to a keyword domain has begun to decrease.
Many online shops have the number 24 in them, to signify 24 hours a day – you may also be able to integrate numbers into your domain in a meaningful way to make them unique. Be careful though, because many cultures attach a lot of significance to certain numbers. Make sure that your number doesn't represent bad luck or other negative things in the country you're operating in.